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Stem Cell Therapy for Lungs

Shortness of breath, persistent coughing, and fatigue are symptoms that can significantly  affect the daily lives of people dealing with lung-related conditions. While traditional treatments focus on managing symptoms, recent advancements in regenerative medicine can open new doors.

Stem cell therapy for the lungs is a promising approach to support lung repair and improve respiratory function. This article explores how stem cell procedures for lungs help address damage, how much  stem cell therapy for lungs costs, and what to expect from this innovative treatment. 

Understanding Lung Conditions and How It Affects Health

Breathing is the process that enables the metabolism of all living cells in the body. When lung function is decreased, it affects overall health and quality of life. Chronic lung conditions often cause progressive damage, making it harder to breathe and perform everyday activities.

Common Types of Chronic Pulmonary Conditions

Chronic obstructive pulmonary disease (COPD)Progressive chronic condition causing airflow blockage. According to the European Respiratory Society, COPD affects 250 million people in the world.
Pulmonary fibrosisThickening of lung tissue due to prolonged inflammation caused by different agents, which impairs oxygen exchange. Research highlights its association with immune dysregulation.
AsthmaBronchospasm or inflammation due to allergens, leading to narrowing of airways and breathing difficulties.
EmphysemaThe lung walls are damaged and lose elasticity; they do not collapse when exhaling, and as a result, gas exchange in the lungs becomes inefficient.

How Lung Damage Affects the Respiratory System

When lung tissue becomes damaged, it loses its ability to expand, contract, and efficiently exchange gases. This can result in reduced oxygen levels in the blood, increased strain on the heart, and chronic fatigue. Modern treatments aim to slow progression, but they can only manage symptoms.

Current Treatment Options for Lung Conditions

Conventional approaches consist of lifestyle changes, medications, and oxygen therapy. These methods manage symptoms, but they do not address the root cause of lung damage. For many patients, alternatives like stem cell therapy for lungs are a promising option.

How Can Stem Cells Help with Lung Conditions?

Stem cells have unique properties that make them ideal for helping to repair damaged tissues. This occurs through their ability to stimulate the differentiation of the body’s own stem cells into specialized cell types; modulation of immune responses; stimulation of blood vessel formation; and stimulating the body towards healing and regeneration.

Potential Benefits of Stem Cell Therapy for Lungs

Research suggests that stem cell therapy for lung disease may:

  • Reduce inflammation and inhibit immune responses in the lung parenchyma. 
  • Stimulate regeneration of damaged cells by synthesizing growth factors, releasing bioactive molecules, and improving metabolism. 
  • Improve overall lung function and respiratory capacity through paracrine activation of natural healing processes.

Can Stem Cell Repair Lung Damage?

While using stem cells for lung repair and regeneration shows promising results, the effectiveness of the treatment varies depending on the condition and individual factors. There is no claim that stem cells are cure-all.

Research suggests that  mesenchymal stem cells for lung regeneration can modulate the immune response and promote tissue repair via bioactive molecules and growth factor secretion.

Stem Cell Therapy for Specific Lung Conditions

Are there any examples of lung disease cured by stem cells? Different lung conditions respond well to stem cell interventions. Below, we explore examples of individual conditions that have experienced notable alleviation of symptoms and quality of life:

Stem Cells for COPD

COPD is a chronic condition caused by tissue damage and inflammation and characterized by obstruction of the airways by thick mucus. Early studies suggest that stem cell therapy for COPD may help with reducing inflammation and improving lung function.

Stem Cell Therapy for Pulmonary Fibrosis

Pulmonary fibrosis is characterized by the replacement of healthy tissue with scar tissue that limits gas exchange in the lungs. Mesenchymal stem cell therapy for pulmonary fibrosis  has shown promise in targeting fibrosis and enabling tissue repair in this condition.

Stem Cells in the Treatment of Asthma

Asthma involves airway inflammation and constriction. Stem cells for bronchial asthma have demonstrated some immunomodulatory properties that may be useful for improving immune responses while reducing inflammation.

Can Stem Cells Help with Emphysema?

Emphysema is characterized by diffuse changes in lung tissue, for example, alveolar damage that impairs oxygen exchange. Stem cell treatment for lungs may potentially provide support and benefits for this lung function. 

Stem Cells for Pneumonia Recovery

Pneumonia often leaves behind residual inflammatory lung damage. Stem cells for lung regeneration could accelerate recovery by promoting tissue repair and reducing inflammation.

Get a free online consultation

If you’ve identified your condition in this list, we invite you to book a no-obligation online consultation with our experts to discuss how stem cell therapy may help improve your lung health and quality of life.

Stem Cell Therapy for Lungs
Dr. Aleksandra Fetyukhina, MD

Medical Advisor, Swiss Medica doctor


What to Expect from Stem Cell Therapy for Lung Disease

The therapeutic effects of stem cell treatment are noticeable 2–6 months after the procedure. During this time, patients experience improvements in lung function, reduced inflammation, and improved overall well-being.

At Swiss Medica, more than 10,000 patients have benefited from stem cell therapy. Of these, 80% have reported good results, demonstrating the exciting efficacy of this advanced practice. This achievement speaks volumes about the dedication and professionalism of our team of stem cell experts and doctors.

Stem Cell Therapy Step by Step

  1. Consultation and Evaluation

    The journey begins with a detailed, free consultation with our specialists to analyze your specific condition and determine if stem cell transplant for lungs is the right solution for you. At this stage, medical professionals review your medical history, conduct diagnostic tests, and discuss your treatment goals.

  2. Harvesting Stem Cells

    Stem cells are extracted from the donor or from the patient’s own body. Common sources of adult stem cell therapy for lungs include bone marrow, adipose tissue, umbilical cord or placenta tissue. These sources are chosen because of their high quality and their ability to promote repair and regeneration.

  3. Preparing and Administering the Stem Cells

    Once collected, the stem cells are processed in a certified lab to ensure safety and sterility. The prepared stem cells are then administered into the lungs through different methods. Local anesthesia may be used as needed for patient comfort.

  4. Monitoring Progress and Follow-Up Care

    After the stem cell delivery procedure, patients are monitored by doctors to ensure safety and address any concerns. In our clinic, there are no more than 3 patients per doctor, which helps to ensure a personalized approach to each patient.

    Follow-up visits are scheduled to track progress, evaluate outcomes, and determine additional treatments when necessary. This is very important for achieving long-term results.

How Stem Cells Are Administered for Lung Repair

Stem cell transplants for the lungs can be delivered through intravenous infusion or directly into the lungs through inhalations. The method depends on the condition being treated.

Stem Cell Therapy for Lungs
Getting stem cells for lung regeneration directly into the respiratory tract leads to a faster onset of their action and activation of the body’s own regenerative processes, which helps to improve the patient’s condition.

Possible Side Effects and Risks

While generally safe, potential risks after stem cell treatment for lungs include mild reactions at the injection site or temporary flu-like symptoms. It’s important to choose a reputable facility with experienced physicians.

In our lab, MSCs are put through a rigorous series of tests before being used in treatments. These tests ensure their purity, viability, and sterility. The tests check for bacterial, fungal, and viral contamination. They also confirm the cells’ identity and function using genetic and molecular testing.

Choosing the Right Clinic for Stem Cell Transplant for Lungs

When choosing a clinic for stem cell therapy for lung repair, it is essential to consider competence, personalized treatment options, and deep patient attention.

Swiss Medica is a leading provider of regenerative medicine, established in 2011. We boast our own state-of-the-art clinical facilities, including a new hospital, a clinic, and our own cutting-edge laboratory, where we are at the forefront of research.

Once you decide to move forward, we’ll make sure you’re well-supported throughout the stem cell lung repair and regeneration process. First, we will thoroughly analyze your lab tests and imaging results to assess your condition. In addition to stem cells for lung disease, our team offers complementary treatments like restorative therapy and physiotherapy to promote healing. We also assist with travel arrangements, accommodations, and meals tailored to your preferences. 

Stem Cell Therapy for Lungs
Stem Cell Therapy for Lungs
Stem Cell Therapy for Lungs
Stem Cell Therapy for Lungs

Our new hotel-style hospital opened in Belgrade in 2024. It is designed for your comfort, equipped with all the necessary medical equipment, and features a dining room where our chefs prepare meals to your individual preferences.

Cost and Availability of Stem Cell for Lung Disease

Depending on the location, reputation of the clinic, and treatment plan, stem cell therapy for lungs costs may vary. Swiss Medica, for example, is located in Belgrade, Serbia and is more accessible than other destinations. Prices generally range between €7,000 and €31,000* per course, including accommodation.

*The prices mentioned are indicative and subject to change based on individual factors, including the condition’s severity and the number of stem cells needed. Prices are valid as of January 2025.

Advances in Stem Cell Research for Lung Regeneration

Recent studies highlight the potential of mesenchymal stem cells for lung regeneration in restoring damaged tissue. Researchers are also exploring techniques to enhance stem cell efficacy.

The Future of Stem Cell Therapy for Lung Disease

Early studies have shown that MSCs are able to regenerate by differentiating into functional lung cells, inhibiting inflammatory progression through immunomodulation and anti-inflammatory functions, and promoting endogenous tissue regeneration through paracrine effects. Mesenchymal stem cell treatment for lung offers hope to those affected by these diseases and are currently the most commonly used stem cells in clinical trials due to their low immunogenicity and tumorigenicity and the lack of potential ethical problems. 

Will Stem Cell Therapy Become a Standard Treatment for Lung Conditions?

While stem cell therapy holds immense potential for addressing the root causes of lung conditions, it is still a relatively new approach and remains under active research. Stem cell treatment for lungs is now used when conventional therapies cannot improve the condition or as an adjunct to conventional therapy.

In order for this treatment to become widespread, key aspects such as the source of stem cells, administration methods, and culture techniques need to be standardized. Despite these challenges, there is evidence that stem cell treatments for lung disease may play a key role in future standards of care. 

Frequently Asked Questions About Stem Cell Therapy for Lung Conditions

Contact us

These may not be all the answers you’ve been looking for. To ask your personal questions and explore how stem cell therapy can help you, book a no-obligation online consultation with our experts today.

Stem Cell Therapy for Lungs
Dr. Aleksandra Fetyukhina, MD

Medical Advisor, Swiss Medica doctor


List of References

  1. Carlo Agostini, Stem cell therapy for chronic lung diseases: Hope and reality, Respiratory Medicine, 2010, Pages S86-S91, ISSN 0954-6111, https://doi.org/10.1016/j.rmed.2010.03.022 https://www.sciencedirect.com/science/article/pii/S095461111000140X

  2. Lu W, Yan L, Tang X, Wang X, Du J, Zou Z, Li L, Ye J, Zhou L. Efficacy and safety of mesenchymal stem cells therapy in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials. J Transl Med. 2024 Jun 8;22(1):550. doi: 10.1186/s12967-024-05358-6. PMID: 38851730; PMCID: PMC11162060.

  3. Wang F, Li Y, Wang B, Li J, Peng Z. The safety and efficacy of mesenchymal stromal cells in ARDS: a meta-analysis of randomized controlled trials. Crit Care. 2023 Jan 20;27(1):31. doi: 10.1186/s13054-022-04287-4. PMID: 36670442; PMCID: PMC9857915.

  4. Zhai, Z., Cui, T., Chen, J. et al. Advancements in engineered mesenchymal stem cell exosomes for chronic lung disease treatment. J Transl Med 21, 895 (2023). https://doi.org/10.1186/s12967-023-04729-9

  5. Sabine Geiger, Daniela Hirsch, Felix G. Hermann. Cell therapy for lung disease,European Respiratory Review 2017 26(144): 170044; DOI: https://doi.org/10.1183/16000617.0044-2017 https://publications.ersnet.org/content/errev/26/144/170044

  6. Silva Kátia Nunes da, Pinheiro Priscila Carvalho Guedes, Gobatto André Luiz Nunes, Passos Rogério da Hora, Paredes Bruno Diaz, França Luciana Souza de Aragão, Nonaka Carolina Kymie Vasques , Barreto-Duarte Beatriz, Araújo-Pereira Mariana, Tibúrcio Rafael, Cruz Fernanda Ferreira, Martins Gabriele Louise Soares, Andrade Bruno B. , Castro-Faria-Neto Hugo Caire de, Rocco Patricia Rieken Macêdo, Souza Bruno Solano de Freitas. Immunomodulatory and Anti-fibrotic Effects Following the Infusion of Umbilical Cord Mesenchymal Stromal Cells in a Critically Ill Patient With COVID-19 Presenting Lung Fibrosis: A Case Report. Frontiers in Medicine, 2021. https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2021.767291 DOI:10.3389/fmed.2021.767291 ISSN: 2296-858X

  7. Mayo Clinic, Regenerative medicine in lung diseases. Clinical trials. https://www.mayoclinic.org/medical-professionals/pulmonary-medicine/news/regenerative-medicine-in-lung-diseases/mac-20483429

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Dr. Lana
Dr. Lana Reviewer

MD, Pediatrician, Regenerative Medicine Specialist

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