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A Seed of Hope for Future Parents: Stem Cell Therapy for Infertility

Infertility is something many couples face, with around 15–17% struggling to conceive. There are options like medication, IUI, and IVF that can help, but stem cell treatment for female infertility is now offering a fresh sense of hope. Similarly, there are promises in the area of male fertility after stem cell transplant.

Let’s explore the scientific principles behind stem cell therapy, its benefits and limitations, as well as the stem cell treatment for female infertility cost and male options for treatment.

Understanding Infertility: Causes and Challenges

Infertility is a complex issue that affects both the male and female reproductive systems, making it difficult to conceive a child. The causes of infertility vary widely and may involve one or both partners.

For women, it might include:

  • Ovulation disorders—conditions like polycystic ovary syndrome (PCOS) disrupt the release of eggs.
  • Endometriosis—a condition where tissue similar to the lining of the uterus (endometrium) grows outside the uterus, often on the ovaries, fallopian tubes, or pelvic lining.
  • Structural issues—abnormalities in the uterus or fallopian tubes can prevent successful fertilisation or implantation.

For men:

  • Sperm issues—difficulties with sperm shape, movement (motility), or low sperm count are leading causes of male infertility.
  • Varicocele—enlarged veins in the scrotum can impact sperm production and quality.
  • Hormonal imbalances—low testosterone levels can affect sperm production.

Infertility, in addition to physical issues, adds new challenges to the patient’s life:

  • Emotional distress—infertility can lead to feelings of sadness, anger, frustration, guilt, depression, and anxiety. 
  • Social stigma—infertility can be isolating and stigmatizing, leading to feelings of shame and inadequacy.
  • Financial strain—fertility treatments can be expensive, placing a significant financial burden on individuals and couples.
  • Time pressure—often referred to as the “biological clock”—can add immense pressure, creating anxiety and limiting treatment options.
  • Relationship strain—infertility can strain relationships, impacting communication and intimacy.

How Stem Cell Therapy Works for Infertility Treatment

Mesenchymal stem cell therapy for infertility provides hope to those seeking to conceive or improve their quality of life by addressing the underlying causes.

The course of stem cell treatment for female infertility allows restoring the ovulation cycle in women while also improving egg quality, uterine lining, fallopian tube blockage, and uterine fibroids. 

As for stem cell therapy for male infertility, it focuses on the normalization of spermogram indicators. The treatment focuses on a process called spermatogenesis. This process helps develop sperm from germ cells in the testis tubules. It starts with the division of stem cells, which encourages the testes to produce more sperm. As a result, sperm counts can significantly increase, gradually improving fertility.

Want to better understand the stem cell treatment process?
Dive into this article for detailed explanations.

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Benefits of Stem Cell Therapy for Infertility

When traditional treatments—like medications and lifestyle changes—don’t seem to work, many find themselves stuck between continuing ineffective treatments and considering other ways to conceive.

How stem cell fertility therapy can help:

  • Encourage producing various growth factors to help needed cells migrate and regulate cell interactions at the molecular level, so the body has the potential to slow the progression of the condition.
  • Activate dormant and suppressed cells, triggering cell division; this way, stem cell fertility treatment may help increase the number of new cells in the body.
  • Secrete various enzymes, cytokines, and proteins that promote cell proliferation and inhibit the death of functional cells.
  • Stem cells have an immunosuppressive function in relation to the body’s natural killer cells.

Are There Any Age Limitations for Stem Cell Therapy for Infertility?

There are age restrictions for using stem cell treatment for female infertility, as age impacts a woman’s chances of conceiving. Menopause, for example, makes pregnancy extremely unlikely, leaving in vitro fertilization (IVF) as the only viable option. However, stem cell therapy can help achieve the desired results for IVF and increase the chances of pregnancy.    

For men, age can impact fertility since sperm quality and quantity tend to decline over time, which may reduce the effectiveness of stem cell treatment for male infertility.

Are There Any Risks or Side Effects with Stem Cell Therapy for Infertility?

Stem cell therapy for infertility is generally considered safe, with most patients experiencing only mild side effects. At Swiss Medica, we find that patients may experience temporary redness or swelling at the injection site, slight fatigue, fever, or a mild headache. Serious complications are uncommon, especially when the therapy is performed in a controlled clinical setting.

After the stem cell fertility treatment, we monitor our patients’ condition for a few days.

Gain a clear understanding of the safety and potential risks of stem cell therapy by reading this article.

Learn more now

Finding the Best Stem Cell Clinic for Stem Cell Treatment for Fertility

Now that you’re aware of the benefits and potential side effects of stem cell therapy, the next step is finding a trusted clinic that offers safe and effective treatment. 

Swiss Medica has a clinic and a newly built hospital in Belgrade, Serbia, where we offer stem cell treatment for female infertility and stem cell therapy for male infertility.

Before coming to our facilities for stem cell treatment, we will schedule a no-obligation online consultation with our medical advisor. During that, we will investigate more about your specific case and may request additional tests. You can ask any questions about the procedure and your future visit to Swiss Medica.

Several days later, our regenerative medicine specialists will develop your personalized treatment plan. During the second online meeting, they will walk you through each step of the treatment.

Our friendly staff will greet you and help you feel at ease in the comfortable, hotel-like atmosphere. During your stay, we focus on your comfort by providing meals that match your dietary preferences, and our staff is available 24/7 to assist you.

A Seed of Hope for Future Parents: Stem Cell Therapy for Infertility
A Seed of Hope for Future Parents: Stem Cell Therapy for Infertility
A Seed of Hope for Future Parents: Stem Cell Therapy for Infertility
A Seed of Hope for Future Parents: Stem Cell Therapy for Infertility
A Seed of Hope for Future Parents: Stem Cell Therapy for Infertility

We have a clinic and a hospital in Serbia, both equipped with modern facilities and an in-house laboratory..

Our lab produces stem cell products that meet strict safety standards. Even though results in terms of fertility after stem cell transplant can vary, we focus on providing reliable care and support as you take steps toward starting or growing your family.

Get a free online consultation

Your choice of clinic matters. Take the first step by filling out the form—our specialists are ready to discuss your options and guide you toward the most suitable treatment.

A Seed of Hope for Future Parents: Stem Cell Therapy for Infertility
Dr. Aleksandra Fetyukhina, MD

Medical Advisor, Swiss Medica doctor


Why Choose Swiss Medica for Stem Cell Treatment for Infertility?

Choosing Swiss Medica for your stem cell therapy means taking a positive step toward better health. Here’s what makes us special:

Personalised Care

We take a personalized approach by growing and preserving both your own cells and donor cells. This allows us to create treatments that are just right for you. We also use different methods to deliver these therapies for your unique situation.

Trusted Expertise

Our team is made up of dedicated professionals and researchers who specialize in female and male fertility after stem cell transplant. With their extensive knowledge and genuine passion for helping patients, you can feel confident that you’re receiving advanced care.

Affordable Solutions

We believe quality healthcare should be accessible. Operating in Serbia allows us to provide mesenchymal stem cells for reproduction at prices lower than many other clinics around the world.

Easy Travel for Patients

Belgrade is easily accessible with its well-connected international flights. We’ll do our best to make your experience easy so you can focus on what really matters—your health and well-being.

Discover what sets our clinic apart in regenerative medicine and why it could be the right choice for you.

Read now

Success Rate of Stem Cell Therapy for Infertility at Swiss Medica

At Swiss Medica, we’re passionate about helping couples regain hope in their journey to start a family. Our dedicated team of stem cell specialists and medical professionals is here to assist you throughout the entire process. We know that the journey to parenthood can be tough, and we’re committed to making it as smooth as possible.

Since we began this journey in 2011, we’ve had the privilege of assisting over 10,000 individuals. We’re proud to say that about 80% of those patients have experienced positive outcomes. Their heartfelt success stories truly inspire us and highlight the difference our work makes.

Cost of Stem Cell Treatment for Infertility

If you’re considering stem cell fertility clinics, our facilities in Serbia are a smart choice. Stem cell treatment for female infertility cost typically ranges from €7,000 to €31,000*, which is much more affordable than at US clinics, where it can reach $50,000.

*The prices mentioned are indicative and subject to change based on individual factors, including the condition’s severity and the number of stem cells needed. Prices are valid as of January 2025.

One of the reasons for this difference is that Serbia has lower overall healthcare costs, which allows clinics to offer competitive pricing. Nevertheless, you can expect excellent care and attention from skilled professionals. Plus, while you’re here, you’ll have the chance to explore the stunning landscapes and rich culture of Serbia.

Real Success Stories: Couples Who Overcame Infertility with Stem Cell Therapy

A more recent clinical trial for stem cells in reproductive medicine explored therapy for women with infertility caused by intrauterine adhesions (IUA)—a leading cause of uterine infertility. IUA results from fibrotic regeneration of the endometrium following severe damage. In this study, 26 women received stem cell therapy using cells from umbilical cords. The cells were placed into the uterus after a procedure to remove the scar tissue.

Three months after the treatment, the patients’ uterine lining had improved, and their adhesions were reduced. After 30 months, 10 women became pregnant, and eight gave birth to healthy babies.

Stem Cells in Reproductive Medicine: Research

Several studies have looked into the use of mesenchymal stem cells (MSCs) to treat fertility, specifically to restore ovarian function in the context of various gynecologic issues. MSCs have been shown to react to damage by traveling to compromised ovaries and assisting in the repair of said damage. This happens because they respond to certain signals in the body.

However, mechanisms of MSCs’ work within the ovary are in the discovery phase and should open more possibilities for reproductive medicine.

Fertility After an Autologous Stem Cell Transplant: Clinical Trials

Here’s a summary of notable clinical trials using stem cells in human reproduction:

  • Valeria Muller, 2017—Used bone marrow stem cells to treat women aged 20–44 with uterine issues affecting fertility.
  • Hesham Elshaer, 2014—Involved injecting umbilical cord stem cells into women aged 18–40 with early menopause to see if it could help them conceive.
  • Guangzhi Liu, 2022—Tested the safety of giving umbilical cord stem cells through an IV to women aged 19–40 with primary ovarian insufficiency.
  • Stem Cells Arabia, 2018—Investigated the use of bone marrow stem cells to help women aged 20–39 with ovarian failure improve their chances of getting pregnant and assess their fertility after stem cell transplant.

FAQ: Stem Cell Treatment for Fertility

Send a request

Learn how stem cell therapy might complement IVF or other fertility treatments. Fill out the form to chat with a specialist today and explore your options.

A Seed of Hope for Future Parents: Stem Cell Therapy for Infertility
Dr. Aleksandra Fetyukhina, MD

Medical Advisor, Swiss Medica doctor


List of References

  1. World Health Organization. 1 in 6 people globally affected by infertility. https://www.who.int/news/item/04-04-2023-1-in-6-people-globally-affected-by-infertility

  2. Lalu MM, McIntyre L, Pugliese C, Fergusson D, Winston BW, Marshall JC, Granton J, Stewart DJ; Canadian Critical Care Trials Group. Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials. PLoS One. 2012;7(10):e47559. doi.org/10.1371/journal.pone.0047559

  3. Esfandyari S, Chugh RM, Park HS, Hobeika E, Ulin M, Al-Hendy A. Mesenchymal Stem Cells as a Bio Organ for Treatment of Female Infertility. Cells. 2020 Oct 8;9(10):2253. doi.org/10.3390/cells9102253

  4. Saeed Y, Liu X. Mesenchymal stem cells to treat female infertility; future perspective and challenges: A review. Int J Reprod Biomed. 2022 Oct 10;20(9):709-722. doi.org/10.18502/ijrm.v20i9.12061

  5. The Time. Meet the World’s First Baby Born With an Assist from Stem Cells. https://time.com/3849127/baby-stem-cells-augment-ivf/

  6. Cao Y, Sun H, Zhu H, Zhu X, Tang X, Yan G, Wang J, Bai D, Wang J, Wang L, Zhou Q, Wang H, Dai C, Ding L, Xu B, Zhou Y, Hao J, Dai J, Hu Y. Allogeneic cell therapy using umbilical cord MSCs on collagen scaffolds for patients with recurrent uterine adhesion: a phase I clinical trial. Stem Cell Res Ther. 2018 Jul 11;9(1):192. doi.org/10.1186/s13287-018-0904-3

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Dr. Lana
Dr. Lana Reviewer

MD, Pediatrician, Regenerative Medicine Specialist

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