Psoriasis, a frustrating and often debilitating skin condition, affects over 120 million people globally. Yet, it still lacks a real solution. Drug treatments help manage symptoms but do not address the underlying cause of the condition. Most therapies try to shut down the body’s overactive inflammation, but this tends to lead to side effects or drug resistance over time.
That is where mesenchymal stem cells (MSCs) can make the difference. These cells contribute to immunomodulation by migrating to skin lesions and reducing autoimmunity. Let us look at how stem cell therapy for psoriasis works in detail.
What Is Psoriasis, and How Does It Affect Your Skin?
Psoriasis is a common skin condition in which damage is caused by different factors, including an overactive immune system, and leads to thick, red, and flaky patches called plaques. These patches can appear on the scalp, elbows, and knees, causing itching and irritation.
Currently, there’s no permanent cure, so patients with psoriasis must manage it throughout their lives. Flare-ups can happen unexpectedly, triggered by factors such as stress, infections, skin injuries, certain medications, and cold weather.
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How Stem Cell Therapy Works for Psoriasis
Stem cell therapy, which is relatively safe and non-invasive, has already proven effective in treating a variety of autoimmune conditions. The mechanics of stem cell infusions for psoriasis, as well as other delivery methods, affect the immune system and the whole body by promoting tissue repair and decreasing inflammation. Let us look at the advantages and detailed process of stem cell therapy for psoriasis.
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Benefits of Stem Cell Therapy for Psoriasis Patients
While it’s not a guaranteed solution, using stem cells to help with psoriasis offers several benefits that can improve how the condition is managed:
- Symptom relief. MSCs has the potential to improve symptoms where traditional treatments fall short, and it offers another option for managing the condition.
- Slows condition progression. Therapy can help to reduce the symptoms and progression of psoriasis.
- Reduced dependence on drugs. MSCs may reduce the need for long-term medication or hardware support by addressing symptoms and the underlying issues.
- Improved quality of life. Patients might experience an overall improvement in their day-to-day well-being, sometimes even longer than with conventional treatments alone.
What Types of Stem Cells Can Treat Psoriasis?
Mesenchymal stem cells for psoriasis show great promise. Donor MSCs work by reducing inflammation and assisting the body’s repair process.
After being introduced into the body, MSCs naturally travel to areas of inflammation. Once there, they release growth factors that support tissue repair. They can activate the body’s own regenerative capabilities, improve blood flow by encouraging new blood vessel growth, and calm the immune system.
Stem Cell Therapy for Psoriasis: Is It Safe?
Stem cell therapy for the treatment of psoriasis is generally seen as safe because of the way MSCs work. They don’t usually trigger immune reactions, making them a lower-risk option. Before being used, these cells are carefully tested to confirm they’re pure and free of any contaminants.
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Stem Cell Therapy vs Traditional Psoriasis Treatments
Here’s an overview of how these approaches compare:
Stem cell therapy | Traditional treatments | |
Effectiveness | Enhances body’s own regenerative capabilities and may offer long-lasting relief | Proven effective for many patients |
Duration of treatment | Could mean fewer sessions if effective | Often requires ongoing treatment and adjustments |
Patient suitability | May suit severe cases unresponsive to other treatments | Suitable for different severity levels |
Side effects | Minimal procedural risks | Creams may irritate the skin; light therapy may raise cancer risk; medications can cause infections |
Long-term management | May reduce ongoing treatment needs if effective | Often require regular management throughout life |
Overall, although still in its early stages, stem cell treatment for psoriasis has the potential to make a greater difference in treating the condition in less time than traditional methods.
Real Results: Success Stories from Psoriasis Patients
A 47-year-old man had been struggling with psoriasis for over two decades, trying various treatments without lasting success. In 2020, he received a stem cell transplant for psoriasis involving three rounds of minimally manipulated umbilical cord-derived mesenchymal stem cells (MM-UC-MSCs). The results were remarkable. Within three months of the first round, his skin had cleared completely, with the redness (erythema) vanishing and no recurrence of the psoriasis.
In another study on stem cell treatment for psoriasis, nearly half of the 17 patients showed a 40% improvement, with some showing almost no symptoms at all. Women seemed to respond better to the treatment, with 67% improving compared to 25% of men. While the results are promising, more research with a larger group of patients is needed to confirm how well this treatment works and why women might benefit more.
Cost of Stem Cell Therapy for Psoriasis
At Swiss Medica, in Serbia, the cost of regenerative stem cell therapy usually falls between €7,000 and €31,000*. This is significantly less expensive than psoriasis stem cell treatment in US clinics, where the cost can reach $50,000. The lower price is mainly due to lower taxes in Serbia, which makes travel, accommodation, and treatment more affordable while still meeting high European standards. So, for visitors, Swiss Medica is a great option for receiving quality care without stretching your budget.
*The prices mentioned are indicative and subject to change based on individual factors, including the condition’s severity and the number of stem cells needed. Prices are valid as of January 2025.
Success Rate of Stem Cell Therapy for Psoriasis at Swiss Medica
Since 2011, we’ve helped over 10,000 patients improve their lives, and we’re proud that around 80% of them have seen fantastic results. If you’re interested, read some inspiring success stories from people who’ve walked a similar path.
At Swiss Medica, our stem cell specialists and medical professionals genuinely care about each patient and go above and beyond to deliver the best care in your journey towards better skin. With their knowledge and experience in stem cell therapy, they will work closely with you to develop a treatment plan tailored to your specific needs for managing psoriasis.
Best Stem Cell Clinic for Psoriasis Treatment with Stem Cells
Before you arrive at our clinic for psoriasis stem cell treatment, we will schedule a no-obligation online consultation with our medical advisor. During that time, we will learn more about your specific case and may request additional tests. You can ask any questions about the procedure and your future visit to Swiss Medica.
Several days later, our regenerative medicine specialists will develop your personalized treatment plan. During the second online meeting, they will guide you through each step.
Upon your arrival, our friendly staff will welcome you. The environment will feel like a high-end hotel rather than a hospital. You’ll be guided by a dedicated team focused on your health and well-being. We also cater for your dietary needs and have staff available 24/7 to support you.
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Depending on the treatment plan, the doctor may determine that the best option is to use your own stem cells for psoriasis treatment. These cells can be safely collected from sources like bone marrow or fat.
Cell products are produced in our in-house lab. It follows strict safety standards when producing products from mesenchymal stem cells for psoriasis treatment to make sure you receive reliable care throughout your stay.
Why Choose Swiss Medica for Stem Cell Therapy for Psoriasis?
At Swiss Medica, we believe your journey to better health should be a positive experience. We provide:
- Tailored care. We grow and preserve your cells, including placental donor cells, to create personalised treatment plans. We also use various delivery methods of stem cells for psoriasis treatment to meet your unique needs.
- Expert team. You can count on our passionate team of experts in regenerative medicine to provide you with outstanding care.
- Affordable options. Quality healthcare shouldn’t be expensive. Our location in Serbia lets us offer mesenchymal stem cells for psoriasis therapy at lower prices than many other clinics, which makes treatment more accessible.
- Convenient travel. Getting to Belgrade is easy with its great international connections. We work hard to make your visit smooth and hassle-free so you can focus on what matters most.
See why patients choose our clinic for advanced therapies and exceptional care — find out what we offer.
Explore nowPsoriasis Stem Cell Treatment Clinical Trials
A review of the British Association of Dermatologists identified several notable psoriasis stem cell clinical trials:
- De Jesus et al. Treatment with autologous ADSCs showed significant skin improvement but needed additional therapies.
- Comella et al. Treatment with autologous SVF achieved complete clearance of psoriasis with no recurrences.
- Seetharaman et al. Topical ADSC-conditioned medium applied for 30 days led to significant improvement in scalp psoriasis.
These MSC-based studies demonstrated promising results for the future treatment of psoriasis. Patients had mild relapses, which responded well to systemic therapy, and no serious adverse events were reported.
Stem Cell Research for Psoriasis
Clinical studies using MSCs show the promise of stem cell therapy for psoriasis by effectively reducing condition severity. Here are the key points:
- Injecting umbilical cord MSCs (UCMSCs) helps lower inflammation by acting on immune cells.
- Injections of adipose-derived stem cells (ADSCs) moderate severe symptoms of psoriasis .
- MSCs from human tonsils can prevent autoimmune responses linked to psoriasis.
- Dermal MSCs from healthy people can counteract inflammation from abnormal MSCs found in psoriatic plaques.
The type of cells used in the therapy is determined by medical professionals and should be based on the results of a thorough examination of the patient’s condition.
FAQ: Stem Cell Treatment for Psoriasis
1. Can stem cell cure psoriasis?
Stem cells offer hope in easing psoriasis symptoms, but they’re not a one-time solution.
2. Can psoriasis fully heal?
Psoriasis is a lifelong condition that is not currently curable; however, with the right treatment, such as using stem cells for psoriasis, it can be well-managed and symptoms improved.
3. What are the side effects of stem cell treatment?
Stem cell therapy side effects are typically mild, such as a low-grade fever for a few hours following the injection. In most cases, patients find the procedure to be simple and free of complications. However, our staff will monitor your condition during your stay at the clinic and keep in touch with you after you return home.
Leave your contact information in the form on our website or send a message to our manager via online chat, and we will assist you in answering your questions and scheduling a free online consultation with a medical advisor.
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Contact us to learn about the expected result for your case, the personal treatment program, its costs and duration.
Medical Advisor, Swiss Medica doctor
List of References
National Psoriasis Foundation. https://www.psoriasis.org/psoriasis-statistics/
Anand S. Srivastava, G. R. Pillai1. Stem Cell Therapy for Treating Autoimmune Diseases (2024). https://onlinelibrary.wiley.com/doi/toc/10.1155/4162.si.716197
Ahn H, Lee SY, Jung WJ, Pi J, Lee KH. Psoriasis treatment using minimally manipulated umbilical cord-derived mesenchymal stem cells: A case report. World J Clin Cases. 2021 Aug 16;9(23):6798-6803. doi.org/10.12998/wjcc.v9.i23.6798
Yang J, Xiao M, Ma K, Li H, Ran M, Yang S, Yang Y, Fu X, Yang S. Therapeutic effects of mesenchymal stem cells and their derivatives in common skin inflammatory diseases: Atopic dermatitis and psoriasis. Front Immunol. 2023 Feb 20;14:1092668. doi.org/10.3389/fimmu.2023.1092668
Cheng L, Wang S, Peng C, Zou X, Yang C, Mei H, Li C, Su X, Xiao N, Ouyang Q, Zhang M, Wang Q, Luo Y, Shen M, Qin Q, Wang H, Zhu W, Lu G, Lin G, Kuang Y, Chen X. Human umbilical cord mesenchymal stem cells for psoriasis: a phase 1/2a, single-arm study. Signal Transduct Target Ther. 2022 Aug 5;7(1):263. doi.org/10.1038/s41392-022-01059-y
Yao D, Ye S, He Z, Huang Y, Deng J, Wen Z, Chen X, Li H, Han Q, Deng H, Zhao RC, Lu C. Adipose-derived mesenchymal stem cells (AD-MSCs) in the treatment for psoriasis: results of a single-arm pilot trial. Ann Transl Med. 2021 Nov;9(22):1653. doi.org/10.21037/atm-21-5028
A. Paganelli, E. Tarentini, L. Benassi, S. Kaleci, and C. Magnoni. Mesenchymal stem cells for the treatment of psoriasis: a comprehensive review. doi.org/10.1111/ced.14269
Chen Y, Hu Y, Zhou X, Zhao Z, Yu Q, Chen Z, Wang Y, Xu P, Yu Z, Guo C, Zhang X, Shi Y. Human umbilical cord-derived mesenchymal stem cells ameliorate psoriasis-like dermatitis by suppressing IL-17-producing γδ T cells. Cell Tissue Res. 2022 Jun;388(3):549-563. doi.org/10.1007/s00441-022-03616-x
MD, Pediatrician, Regenerative Medicine Specialist
Medical Advisor, Swiss Medica doctor