Multiple sclerosis is a chronic autoimmune condition that tends to progress over a period of time affecting the patient’s routine life. Currently, there is no cure for multiple sclerosis. However, recent research has revealed that MS stem cell treatment might provide potential therapeutic options for patients diagnosed with this condition.
This article is aimed at evaluating the effectiveness and safety of MS stem cell treatment. We will also learn the benefits of stem cells for multiple sclerosis treatment, how mesenchymal stem cell infusion therapy works in the management of this condition, and the treatment options at Swiss Medica clinic, one of the most reputable clinics in the field located in Serbia.
Why Use Stem Cells to Treat Multiple Sclerosis?
Multiple sclerosis is an autoimmune condition. It occurs when the immune system fails to recognize the body’s own cells and tissues as its own. As a result, the immune system mounts an attack on these tissues resulting in their destruction.
Multiple sclerosis affects the nervous system and damages the myelin sheath covering the nerve fibers due to which the communication between the brain and the other parts of the body is affected. This can prevent a person from performing routine tasks in an efficient manner, reducing the quality of his life.
In addition, the patient also experiences symptoms, such as:
- Weakness
- Difficulty speaking
- Chronic pain
- Tingling and numbness in the hands and legs
- Vision loss as disease progresses
These symptoms can create a negative impact on the patient’s personal life, academics, and career, putting him at risk of mental health issues, such as anxiety and depression.
Unfortunately, currently, there is no cure for multiple sclerosis. Although there are several medications to treat MS, most of them have serious side effects. Some medications, especially corticosteroids, prescribed to suppress the activities of the immune system stop working over a period of time.
Challenges associated with the management of multiple sclerosis emphasize the need to find advanced treatment options to help patients get relief from the symptoms and avoid the complications associated with nerve damage.
Fortunately, research on stem cell therapy for MS shows promising results in the management of this condition. Stem cell therapy is expected to improve the prognosis of multiple sclerosis by regulating the immune system responses and promoting the healing of damaged nerves and myelin sheath.
This is expected to slow down the progression of neurological impairment and provide significant relief from the symptoms of this condition.
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You’ll discover:
1. Will stem cell therapy be beneficial for your case?
2. What improvements can you expect, and when?
2. What is the success rate of the therapy?
3. What is included in the stem cell treatment plan?
5. How much does stem cell therapy for MS cost?
6. What is the typical duration of the treatment?
Medical Advisor, Swiss Medica doctor
What are the Benefits of Stem Cell Therapy for MS?
People may consider MSCs for multiple sclerosis stem cell as cure, , but their benefits are primarily due to their anti-inflammatory, regenerative, immunomodulatory, and healing properties:
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MSCs work by producing an immunomodulatory effect. These cells have the ability to inhibit the autoimmune response of the immune system against nerve fibers. This can help prevent the self-destructive activities of the immune cells, protecting nerve tissue against further damage.
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In addition, the mesenchymal stem cells can protect the nerve cells against damage by pro-inflammatory compounds released by the immune system, including cytokines and interleukins. The anti-inflammatory effect of stem cells can also contribute to relieving pain associated with multiple sclerosis.
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The regenerative potential of stem cells plays a role in inhibiting as well as reversing the pathogenesis of multiple sclerosis. The mesenchymal stem cells transplanted during stem cell therapy can divide and mature to form new cells that can take the place of the damaged cells of the nervous tissue. This might restore neurological functions in patients with this condition.
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These benefits of stem cell therapy are further supported by the ability of MSCs to promote healing. This can improve the normal functions of the affected tissues and allow patients to perform routine activities with better ease.
What Types of Stem Cells Can Treat MS?
Patients with multiple sclerosis are usually treated with mesenchymal stem cells. These are multipotent stem cells that have the ability to differentiate and mature to form a wide range of cell types in the body.
Once transplanted, these stem cells can develop to form healthy nerve cells thus supporting the regeneration of the damaged tissues of the nervous system.
In some cases, specialized cells such as neural stem cells may be used for the treatment of multiple sclerosis. These cells can give rise to several types of cells in the nervous system, thus improving the prognosis of the disease.
Mesenchymal Stem Cell Infusion for Multiple Sclerosis
Although treating multiple sclerosis with stem cells is not a cure to this condition, MSCs infusion has been shown to possess the potential to improve the outcomes of stem cell therapy in patients with multiple sclerosis.
Stem cell injections for MS typically involve isolating mesenchymal stem cells from the patient’s or donor’s bone marrow. The cells are then infused into the patient’s body through blood or spinal fluid, so they produce different cell types in the body, including nerve cells, muscles, and cartilage.
A number of clinical trials worldwide are exploring the potential of stem cell injections for MS. Preliminary research indicates that MSCs transplantation for MS may influence the immune system in a positive way. This could block the self-destructive autoimmune response of the body against the myelin sheath.
This way, although managing multiple sclerosis with stem cells is not a cure, this therapy can provide symptom relief and lower neurological impairment.
How Does Multiple Sclerosis Stem Cell Therapy Infusion Work?
Multiple sclerosis stem cell therapy involves the infusion of autologous stem cell transplant for multiple sclerosis (the patient’s own) or allogeneic stem cells (from the donor) into the patient’s body through an intravenous (IV) drip. This method allows the stem cells to circulate throughout the body, including the nervous system.
Once transplanted, the stem cells migrate to areas of inflammation or damage within the central nervous system (CNS). They are naturally attracted to the sites of injury where the immune system is attacking the myelin sheath, the protective covering of nerve fibers.
The stem cells work by promoting the repair and regeneration of damaged myelin, potentially restoring function to affected nerve cells. They may also differentiate into various cell types needed to replace lost or damaged tissue.
Also, these cells attempt to inhibit the autoimmune activities responsible for triggering self-destructive activities against the tissues of the nervous system. The reformatting of the immune system lowers the secretion of pro-inflammatory compounds by the immune system. This helps lower inflammation in the nerve cells, myelin sheath, and other tissues of the nervous system. Thus, MSCs can improve the symptoms of multiple sclerosis, lower the risk of frequent relapses, and potentially slow down the progression of the disease.
It is important to note that continuous monitoring of the patient during multiple sclerosis stem cell therapy is a critical aspect of this treatment for ensuring its safety and effectiveness. Also, the frequency and duration of stem cell infusion need to be determined based on the severity and duration of the condition and the extent of involvement of the nerve cells.
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For more information about cell therapy, including specifics such as:
1. How injected stem cells act?
2. How the graft overcomes the blood-brain barrier?
3. The safety issues of therapy
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Medical Advisor, Swiss Medica doctor
Can Stem Cells Cure Multiple Sclerosis?
Currently, there is no evidence to prove stem cell cure for MS. However, it can definitely help relieve the symptoms and improve the functions of the nerves and other tissues of the nervous system by producing regenerative, immunomodulatory, and anti-inflammatory effects. However, stem cell cure for MS remains the research area for scientists.
Complications and Side Effects in MS Stem Cell Treatment
MS stem cell treatment is usually safe and not known to cause serious or long-term side effects. However, some patients may develop mild symptoms during and after the therapy.
Some common side effects of allogeneic and autologous stem cell transplant for multiple sclerosis include fever, pain, redness, and irritation at the site of injection. These symptoms are usually temporary and tend to resolve spontaneously over a period of a few days.
Complications are rare and may include post-infusion infections and immune reactions like Graft-versus-Host Disease (GVHD), where the donor cells attack the patient’s body, and autoimmune responses.
Stem Cell Research for Multiple Sclerosis
Stem cell research on multiple sclerosis and stem cell transplant is a rapidly evolving field that holds significant promise for developing new treatments and potentially finding a cure for this chronic neurological condition. Studies explore the benefits of hematopoietic, mesenchymal, and induced pluripotent stem cells.
One of the significant challenges in stem cell therapy is the potential for immune rejection, particularly when using donor cells. Research is ongoing to develop methods to reduce this risk, such as using autologous (patient’s own) stem cells or genetically modified cells. The use of bioengineered stem cells and gene editing technologies like CRISPR may improve the effectiveness of stem cell therapies.
The National Multiple Sclerosis Society, along with other organizations, is actively funding and supporting research into mesenchymal stem cell therapy for multiple sclerosis to explore their potential and improve treatment protocols. The goal is to develop safer and more effective ways to use stem cells in treating MS. Currently, stem cell therapies for MS are still considered experimental and have not been widely approved as standard treatment options. Patients are encouraged to participate in clinical trials to access these innovative therapies and contribute to advancing research in this field.
What’s the Outlook for Stem Cell Therapy for Multiple Sclerosis?
Multiple sclerosis treatment with stem cells has shown promising results, offering hope to patients who may not have responded well to conventional therapies.
Ongoing research and clinical trials show that mesenchymal stem cell therapy for multiple sclerosis can reduce relapses, slow disease progression, and improve neurological function in MS patients as well as restore lost function and reduce symptoms.
Other key points on outlook of multiple sclerosis treatment with stem cells include:
- Research on various types of stem cells, including induced pluripotent stem cells (iPSCs) and neural stem cells, to find the most effective treatment for MS.
- Combining stem cell therapy with other treatments, such as immunomodulatory drugs or neuroprotective agents, to enhance the effectiveness of the therapy.
- Studying the long-term safety of stem cell therapy for MS.
- Personalized treatments tailored to individual patients’ genetic profiles, disease characteristics, and response to therapy.
- Providing stem cell treatments to more people.
Where to Get Stem Cell Therapy for MS?
If you’re considering stem cell therapy for multiple sclerosis, several options are available depending on your location and specific needs. Here are some key places to look for stem cell therapy for MS:
- Specialized clinics and hospitals
- International clinics
- Research institutions conducting clinical trials
You can get MS stem cell treatment at the Swiss Medica clinic. The stem cell experts with profound experience in regenerative medicine will ensure you receive personalized treatment and all-inclusive experience to manage your symptoms and avoid the potential complications of this condition.
Best Stem Cell Clinic for MS Stem Cell Treatment
If you are looking for where to get MS stem cell treatment, you can reach out to our experts at Swiss Medica.
Swiss Medica offers advanced stem cell therapy for MS. You can get a free consultation with our experts to learn whether stem cells can help improve MS symptoms and find out the benefits and potential side effects of stem cell infusion for managing your condition.
Why Choose Swiss Medica for a Multiple Sclerosis Stem Cell Cure
Here is what makes Swiss Medica the right choice:
- A team of stem cell experts and other medical professionals with a profound experience in regenerative medicine;
- The treatment plan tailored to your individual characteristics and needs;
- All-inclusive experience, including travel assistance and medical guidance;
- A comfortable hotel-like setting in a clinic with friendly medical team;
- In-house laboratory providing fresh stem cells and rigorous quality control;
- Convenient European location of the clinic;
- Wide variety of ethical stem cells provided by various delivery methods for greater efficiency.
The Success Rate of MS Stem Cell Treatment at Swiss Medica
Up to 80% of our patients experience improvements from their symptoms while restoring the normal functions of the nervous system.
Many notice positive changes during and after MS stem cell treatment at Swiss Medica, and you can hear their stories directly from them or check the review at our YouTube channel.
Our clinic often receives new patients through word-of-mouth referrals, and those patients frequently recommend us to others. With consent, you also have the option to contact our previous patients directly, ask further questions, and gain an objective, third-party perspective on multiple sclerosis stem cell therapy.
Real Patient Stories
Reviews from people treating MS with stem cells is the best proof of its efficiency and safety. Here are reviews from patients of the Swiss Medica clinic.
Story of a Patient from England
The patient traveled from England seeking relief from his MS symptoms, a condition he has battled since 2006. Over the years, he has struggled with fatigue, mobility issues, and complications with his bladder and bowel, all stemming from nerve damage.
After conducting thorough research with his wife, they discovered numerous positive reviews from Swiss Medica patients. His treatment experience was smooth. He also appreciated that his travel, accommodations, and vegetarian dietary preferences were thoughtfully arranged.
“The medical staff were outstanding, especially the doctor. Everything was clearly explained, and they were thorough in their checks. I would definitely recommend this place.”
Feedback from the patient from Romania
The patient traveled from Romania seeking treatment for MS after hearing positive feedback about stem cell therapy for the disease. He had severe balance issues, couldn’t walk, and needed assistance with daily tasks like eating. Despite trying other treatments, including injections and infusions of various medications, he saw no significant improvement.
However, after the first round of stem cell therapy at Swiss Medica, the patient noticed improvements: he can now raise his left arm, has better body balance, and his double vision has significantly decreased, with his eyes becoming straighter just three days after the treatment. He also appreciated the caring attitude of the doctors.
“It’s already started to show good results, so I hope it will be much better.”
Stem Cell Therapy for MS Cost
The average stem cell therapy for MS cost depends on various factors like severity of multiple sclerosis and stem cell transplant types, location and extent of treatment, pre- and post-treatment care, travel and accommodation. The stem cell experts at our clinic will determine the final list of procedures needed to manage your condition based on your symptoms and investigation reports and provide an estimate of the costs, which usually range from €7,000 to €25,000.
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Get a free online consultation to learn how stem cells will work for your case, and what are the duration and cost of the therapy.
Medical Advisor, Swiss Medica doctor
Frequently Asked Questions about MS Stem Cell Treatment
1. What is multiple sclerosis (MS)?
Multiple sclerosis is a chronic autoimmune disease in which the immune system attacks the protective myelin sheath that covers nerve fibers, causing communication problems between the brain and the rest of the body. This can lead to permanent nerve damage or deterioration. Symptoms may include fatigue, walking and balance difficulties, vision problems, numbness in some body parts, and others.
2. What is stem cell therapy for MS?
Stem cell treatment for MS involves infusing stem cells into the patient’s body to repair or replace damaged cells in the nervous system. This therapy aims to reduce the immune system’s abnormal attack on the nervous system, which is a key factor in the progression of MS. By promoting immune tolerance and reducing inflammation, stem cells help to slow down the disease’s progression and alleviate symptoms, leading to potential improvements in patients’ quality of life.
3. What to expect after stem cell therapy for MS?
Here are some positive outcomes you can expect after stem cells for MS treatment:
- – Reduced disease activity: Some patients experience a significant reduction in disease activity and relapse rates.
- – Improved symptoms: Improvement in symptoms, such as fatigue, pain, and mobility issues, can be experienced by treating MS with stem cells.
- – Potential remission: In some cases, stem cells for MS treatment can lead to a long-term remission of the condition.
4. Who is a candidate for stem cell treatment for MS?
Candidates for stem cell treatments for MS typically include patients with aggressive relapsing-remitting MS (RRMS) who have not responded well to conventional treatments.
Patients with primary progressive MS (PPMS) or secondary progressive MS (SPMS) can also consider multiple sclerosis stem cell treatment if there is evidence of ongoing inflammatory activity.
List of References
Lemus, H. N., Warrington, A. E., & Rodriguez, M. (2018). Multiple Sclerosis: Mechanisms of Disease and Strategies for Myelin and Axonal Repair. Neurologic clinics, 36(1), 1–11. https://doi.org/10.1016/j.ncl.2017.08.002
Tafti, D., Ehsan, M., & Xixis, K. L. (2024). Multiple Sclerosis. In StatPearls. StatPearls Publishing.
Uccelli, A., Laroni, A., Brundin, L., Clanet, M., Fernandez, O., Nabavi, S. M., Muraro, P. A., Oliveri, R. S., Radue, E. W., Sellner, J., Soelberg Sorensen, P., Sormani, M. P., Wuerfel, J. T., Battaglia, M. A., Freedman, M. S., & MESEMS study group (2019). MEsenchymal StEm cells for Multiple Sclerosis (MESEMS): a randomized, double blind, cross-over phase I/II clinical trial with autologous mesenchymal stem cells for the therapy of multiple sclerosis. Trials, 20(1), 263. https://doi.org/10.1186/s13063-019-3346-z
Gugliandolo, A., Bramanti, P., & Mazzon, E. (2020). Mesenchymal Stem Cells in Multiple Sclerosis: Recent Evidence from Pre-Clinical to Clinical Studies. International journal of molecular sciences, 21(22), 8662. https://doi.org/10.3390/ijms21228662
Zolfaghari Baghbadorani, P., Rayati Damavandi, A., Moradi, S., Ahmadi, M., Bemani, P., Aria, H., Mottedayyen, H., Rayati Damavandi, A., Eskandari, N., & Fathi, F. (2022). Current advances in stem cell therapy in the treatment of multiple sclerosis. Reviews in the neurosciences, 34(6), 613–633. https://doi.org/10.1515/revneuro-2022-0102
Rahim, F., Arjmand, B., Tirdad, R., & Saki Malehi, A. (2019). Stem cell therapy for multiple sclerosis. The Cochrane Database of Systematic Reviews, 2019(9), CD013049. https://doi.org/10.1002/14651858.CD013049.pub2
Gugliandolo, A., Bramanti, P., & Mazzon, E. (2020). Mesenchymal Stem Cells in Multiple Sclerosis: Recent Evidence from Pre-Clinical to Clinical Studies. International journal of molecular sciences, 21(22), 8662. https://doi.org/10.3390/ijms21228662
MD, Pediatrician, Regenerative Medicine Specialist