Stem Cells for Peyronie's Disease

Peyronie’s disease (PD) is a connective tissue disorder of the penis characterized by fibrosis and the formation of plaque within the tunica albuginea, leading to penile curvature, shortened penis size, and erectile dysfunction. The fibrotic disorder has a prevalence rate of 3.2% among middle-aged men between 40–59 years.

Stem cells for Peyronie’s disease present a noninvasive treatment option for PD patients, with promising results. These undifferentiated cells have the remarkable ability to self-renew and differentiate, which promotes healing of the scarred tissues, while producing anti-inflammatory and immunomodulatory effects.

Let’s look at Peyronie’s stem cell treatment, its efficacy, risks and benefits, success rate, cost, and some success stories from our patients.

Why use stem cells to treat Peyronie’s disease?

Stem cells as a regenerative medicine offer a great opportunity to manage the disease and prevent its progression. Stem cells allow for the prevention of disease progression, reduction of inflammation, and the ability to delay or prevent complications, primarily erectile dysfunction. Stem cell Peyronie’s results indicate their potential in treating microvascular trauma.

What are the benefits of stem cell therapy for Peyronie’s disease?

The use of stem cell therapy for Peyronie’s disease offers the following benefits:

Stem cells for Peyronie’s disease help slow down and limit the progression, support the body in fighting the condition, reduce inflammation, and, most importantly, prevent the onset of erectile dysfunction.
Stem cells release anti-inflammatory cytokines that reduce chronic inflammation, alleviate symptoms, and prevent further tissue damage. This helps relieve the pain and discomfort associated with the disease.
Peyronie’s disease stem cell treatment helps modulate immune reactions, eliminating the autoimmune component of the disease, which is considered the main contributor to plaque formation and disease progression.
Stem cells for Peyronie’s disease enhance erectile function by healing damaged tissues and improving blood flow to the penis.
Stem cell therapy for Peyronie’s disease avoids the use of invasive surgeries and can be administered through injections, which allows less recovery time.
Other benefits of stem cell Peyronie’s results include addressing the underlying cause.

What types of stem cells can treat Peyronie’s disease

Stem cell therapy for Peyronie’s disease can involve various types of stem cells, for instance:

Mesenchymal stem cells: MSCs can be harvested from bone marrow, adipose (fat) tissue, and umbilical cord tissue. These cells have anti-inflammatory properties with the ability to differentiate into various cell types, such as fibroblast and micro fibroblasts, making them the best option for PD treatment.
Adipose-derived stem cells: These cells are extracted from the patient’s own fat tissue. They are known for their regenerative and anti-inflammatory abilities, which can help remodel fibrotic tissue.
Bone Marrow-Derived Stem Cells (BMSCs): These cells can be obtained from the patient’s bone marrow. BMSCs are known for their ability to differentiate into various cell types and their potential to enhance tissue repair and regeneration.
Induced Pluripotent Stem Cells (iPSCs): This type of cells can be directly generated from other adult cells, such as skin or blood cells. iPSCs can differentiate into any cell type, which can be beneficial for regenerative therapies. However, their use is still experimental in the context of Peyronie’s disease.
Umbilical Cord-Derived Stem Cells: These stem cells are collected from the donor umbilical cord blood or tissue after childbirth. They have potent anti-inflammatory properties and can stimulate the body’s own repair mechanisms.

Get a free online consultation

Dr. Aleksandra Fetyukhina, MD

Medical Advisor, Swiss Medica doctor

Side effects of stem cell therapy for the treatment of Peyronie’s disease

While stem cell therapy shows promise in treating PD, there are some risks associated with the Peyronie’s disease stem cell treatment, such as:

Pain and discomfort at the injection site
Temporary swelling and redness
Light bruising around the injected area
Risk of infection, as with any procedure involving injections

Some serious risks associated with the disease can be:

Immune response to the injected stem cells for Peyronie’s disease, leading to inflammation or rejection
Allergic reactions to the preservatives used as stem cell medium
Increased production of fibrosis due to improper administration during stem cell treatment for Peyronie’s disease

Best stem cell therapy for Peyronie’s disease

There’s no one Peyronie’s disease stem cell therapy that’s considered the best yet. Among the various types of stem cell therapies explored, the use of mesenchymal stem cells appears to be the most promising. Here’s why:

Anti-Inflammatory properties: This effect can help reduce the inflammation caused by Peyronie’s disease, potentially leading to a decrease in pain and swelling.
Regenerative properties: MSCs can differentiate into various cell types and secrete growth factors, promoting the repair and regeneration of damaged tissues.
Source and Safety: MSCs can be easily harvested from the patient’s own body, typically from bone marrow or fat tissue. Using this type of stem cells minimizes the risk of immune rejection and complications.
Positive outcomes after the treatment: Patients have reported improvements in penile curvature, erectile function, and quality of life after Peyronie’s stem cell treatment.

The success rate of stem cell therapy for Peyronie’s disease at Swiss Medica

Established in 2011, Swiss Medica takes pride in being one of the best clinics offering cell-based therapies, including Peyronie’s disease stem cells, with highly qualified doctors and experts. At Swiss Medica, most cases treated at the clinic has resulted in success due to:

Board-certified physicians and experienced practitioners who engage in continuous stem cell research of Peyronie’s to stay updated with later advancements.
Compliance with regulations and recognized medical accreditations.
Transparent and ethical practices.
State-of-the-art facilities and equipment.
Personalized treatment plan along with a comprehensive pre- and post-care.
Continuous support and regular follow-up care.

Can Peyronie’s stem cells therapy cure the disease?

Stem cells are not considered the definitive cure for PD; however, it is a promising alternative to the traditional options. It’s important to note that the effectiveness of Peyronie’s disease stem cell treatment can vary from patient to patient depending on the patient’s age, the types of cells used, and the severity of the disease.

Cost of stem cell therapy for Peyronie’s disease

The cost of stem therapy can depend on a number of factors, including:

Type of stem cells used
Number of treatments
Additional procedures
Location of the clinic
Travel and accommodation costs

At Swiss Medica, the cost of stem cell therapy for Peyronie’s disease typically ranges between €7,000 and €31,000*, offering a more competitive option compared to many other clinics. To find out what the final cost is, we encourage you to book a free, no-obligation consultation with our experts and discuss your case.

*The prices mentioned are indicative and subject to change based on individual factors, including the condition’s severity and the number of stem cells needed. Prices are valid as of January 2025.

Stem cell research for Peyronie’s disease

Stem cells for Peyronie’s disease is an evolving field of regenerative medicine and a promising area of research. The therapy aims to utilize stem cells’ regenerative capabilities to reduce fibrosis, promote tissue repair, and improve penile curvature and function.

Ongoing clinical studies are exploring:

The best types of stem cells to use
Optimal delivery methods
Potential outcomes for patients

Studies are focusing on the long-term results of stem cell therapy to ensure sustained benefits and reveal any potential risks associated with this treatment.

Innovative approaches include:

Combination Therapies: Studies are aimed to reveal the potential of combining stem cell therapy with other treatments, like collagenase injections, to improve treatment results.
Biomaterials and scaffolds: The use of biomaterials and scaffolds can support stem cell delivery and improve the effectiveness of stem cell treatments.

Stem cell for Peyronie’s disease clinical trials

In 2017, a study used adipose-derived stem cell treatments in patients suffering from Peyronie’s disease. Patients were injected with 5 injections over the period of two months, and stem cell Peyronie’s results showed improvements in the curvature of the penis, reduction in the size of the plaque, and improvements in erectile function.

Recent advancements in Peyronie’s disease stem cells treatment highlight the widespread use of adipose-derived stem cells. These cells are favored due to their abundant availability and the straightforward process of isolation from fat tissue. Multiple studies show that stem cell therapy, including ADSCs, may become a potential treatment and ways to prevent fibrotic diseases like PD.

Real patient stories

At Swiss Medica, we’ve launched a YouTube channel with reviews from our patients. There, patients share their experience and improvements after the treatment at our clinic. Let’s look at many success stories of patients who got treated from various diseases, including fibrotic diseases, and are now living a healthy life.

Why choose Swiss Medica for the best stem cell therapy for Peyronie’s disease?

Founded in 2011, Swiss Medica is now a well-known name in the stem cell therapy field for its quality and effective treatment. Here are a few more reasons why Swiss Medica should be your first choice:

Our team of doctors and researchers is versed in stem cells for Peyronie’s disease research and cutting-edge technology.
Our team carefully studies each case, evaluates the symptoms, and curates a personalized treatment plan, including pre-and post-care.
Our in-house laboratory works in accordance with international standards and ethical guidelines for producing high-quality live stem cell products.
Our clinic is equipped with all necessary medical facilities and provides a comfortable hotel-like setting.
Our team adheres to strict quality control standards at every stage of the therapy.
Our clinic is conveniently located in Serbia and provides travel assistance.

Frequently asked questions about Peyronie’s disease stem cells cure

1. What is the common cause of Peyronie’s disease?

The most common causes of PD are repetitive trauma or injury to the penis, mostly during sexual activity, especially with painful or incomplete erections. Also, other minor injuries to the penis caused by sports or other accidents may cause this condition. The trauma can lead to bleeding and the formation of scar tissue, resulting in erectile dysfunction and pain.

2. Can Peyronie’s disease be reversed?

Peyronie’s disease cannot be reversed. In a very few cases, this disease goes away without treatment. However, to improve erectile function, reduce pain, and curvature following treatments can be helpful:

Oral drugs and physical therapy
Stem cells for Peyronie’s disease into the scar tissue
Surgery to straighten the penis
Collagenase injections
Lifestyle changes

3. Is it possible to recover from Peyronie’s disease?

There’s no cure for PD. However, the symptoms can be managed, and the progression of the disease can be stopped. There are medications and traditional invasive surgery options available. Due to advances in regenerative medicine, mesenchymal stem cells have the potential to become one of the best stem cell therapies for Peyronie’s disease due to their efficacy and safety.

Contact us

You can contact our Medical Advisor to find out about the expected results of stem cell treatment according to your case, its cost, duration, and some other details.

Dr. Aleksandra Fetyukhina, MD

Medical Advisor, Swiss Medica doctor

List of References

Dellis, A., & Papatsoris, A. (2017). Stem cell therapy for the treatment of Peyronie’s disease. Expert Opinion on Biological Therapy, 17(4), 407–413. https://doi.org/10.1080/14712598.2017.1295034
Sangkum, P. (2016). Research highlights on stem cell therapy for the treatment of Peyronie’s disease. Translational Andrology and Urology, 5(3), 363–365. https://doi.org/10.21037/tau.2016.03.14
Dellis, A., & Papatsoris, A. (2017b). Stem cell therapy for the treatment of Peyronie’s disease. Expert Opinion on Biological Therapy, 17(4), 407–413. https://doi.org/10.1080/14712598.2017.1295034
Hilton, L. (2020, November 16). Stem cells pose risk, offer promise for ED, other diseases. Urology Times. https://www.urologytimes.com/view/stem-cells-pose-risk-offer-promise-ed-other-diseases
Gur, S., Abdel-Mageed, A. B., Sikka, S. C., & Hellstrom, W. J. (2018). Advances in stem cell therapy for erectile dysfunction. Expert Opinion on Biological Therapy, 18(11), 1137–1150. https://doi.org/10.1080/14712598.2018.1534955
Moussa M, Abou Chakra M, Moussa Y. Advances in stem cell therapy for the treatment of Peyronie’s disease. Intractable Rare Dis Res. 2020 Feb;9(1):10-13. doi: 10.5582/irdr.2019.01130. PMID: 32201669; PMCID: PMC7062597.

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